Fed up with forehead lines, frown lines and crow’s feet? Wrinkle relaxers like Botox, Dysport, Jeuveau and Daxxify can soften these lines and give you a smoother, more refreshed appearance. They don’t stop aging, but they’re among the most effective non-surgical options for men and women who are bothered by lines and wrinkles in the upper face.
With four excellent options available, the natural question is: which one is right for you? Below, our aesthetic injection specialists break down how each wrinkle relaxer works, how they differ and how we help you choose during your consultation.
What Are Wrinkle Relaxers?
All four of the wrinkle relaxers we offer are injectables made from botulinum toxin type A. They work by temporarily relaxing the muscles responsible for dynamic wrinkles, the lines that form when you make expressions like frowning, squinting or raising your eyebrows. When those muscles relax, the overlying skin smooths out, softening existing lines and helping prevent new ones from deepening.
While Botox, Dysport, Jeuveau and Daxxify share this core purpose, they differ in formulation, how quickly they take effect, how they spread and how long results last. Those differences are exactly why a personalized consultation matters.
Botox Cosmetic
Botox is the original and most widely recognized wrinkle relaxer, FDA-approved for cosmetic use for over two decades. It smooths lines in the forehead, between the eyebrows (the “11s”) and around the eyes (crow’s feet).
During treatment, your injector places very small amounts of Botox directly into the targeted muscles. This temporarily relaxes the muscle, softening the lines created by repeated movement. Results typically appear within 5 to 7 days and last about 3 to 4 months, though this varies from patient to patient. Side effects are usually mild and temporary, such as slight swelling, bruising or redness at the injection sites. Botox remains the gold standard and a great choice for first-timers and precision work.
Dysport
Dysport is also FDA-approved for treating frown lines, crow’s feet and forehead lines. The main difference is that Dysport tends to spread a bit more and has smaller molecules, which can lead to faster onset, with many patients noticing results in about 2 to 3 days. That spread also makes Dysport a strong option for larger treatment areas like the forehead. Duration is comparable to Botox, around 3 to 4 months.
Jeuveau
Jeuveau (sometimes called “Newtox”) is the newest-generation neuromodulator developed specifically for aesthetic use, unlike Botox and Dysport, which also have therapeutic medical applications. It’s made using a modern purification process and performs very similarly to Botox, with onset in about 2 to 5 days and results lasting 3 to 4 months. Unit dosing is essentially the same as Botox.
Daxxify
Daxxify is the longest-lasting wrinkle relaxer available. FDA-approved in 2022 for frown lines, it uses a unique peptide-based formulation (rather than human- or animal-derived proteins) that helps it bind longer.
Daxxify is an excellent option for patients who want to stretch the time between appointments, or who have an event coming up and want results quickly. Some patients even use Daxxify for major areas through the busier fall and winter months, then switch to Botox or Jeuveau for touch-ups.
| Wrinkle Relaxer | Onset | Duration | Often Best For |
|---|---|---|---|
| Botox | 5 to 7 days | 3 to 4 months | First-timers, precise/targeted areas |
| Dysport | 2 to 3 days | 3 to 4 months | Larger areas, faster onset |
| Jeuveau | 2 to 5 days | 3 to 4 months | Preventative treatment, budget-conscious patients |
| Daxxify | 1 to 2 days | About 6 months | Longest-lasting results, fewer appointments |
Onset and duration vary by individual, dosing and treatment area. Your injector will recommend the best option for your goals during your consultation.
How Do I Choose the Right Wrinkle Relaxer?
Here’s the reassuring truth: these products are more alike than different, and the right choice often comes down to how your face responds and how long you want results to last. Many patients even use different products for different areas, or switch over time. Above all, the skill and experience of your injector matters more than the product itself. That’s where we come in. During your consultation, our aesthetic injection specialists examine your skin, review your medical history and discuss your goals to recommend the wrinkle relaxer (or combination) that’s right for you.
Frequently Asked Questions
Which wrinkle relaxer lasts the longest?
Daxxify typically lasts the longest, around 6 months, thanks to its peptide-based formulation. Botox, Dysport and Jeuveau generally last 3 to 4 months.
Which one works the fastest?
Daxxify and Dysport tend to have the fastest onset (often 1 to 3 days), while Botox usually takes 5 to 7 days to show full results.
How much do wrinkle relaxers cost?
Pricing depends on the product and the number of units needed for your treatment areas. We’ll provide a personalized quote at your consultation. You can also view our current pricing.
Do you offer Xeomin or Letybo?
You may have heard of two other FDA-approved wrinkle relaxers: Xeomin and Letybo. Xeomin (incobotulinumtoxinA) is a “pure” botulinum toxin that contains no accessory proteins, which can appeal to patients who’ve developed resistance to other formulas. Letybo (letibotulinumtoxinA) is a newer, South Korean neuromodulator approved for frown lines, known for a fast onset and natural-looking results.
We’ve intentionally built our wrinkle relaxer menu around Botox, Dysport and Daxxify because these three cover the full range of patient needs, from the gold-standard precision of Botox to the extended duration of Daxxify, and let our specialists tailor the right approach for your face and goals.
If you’re curious how any of these options compare for you, our injectors are happy to walk through all of them at your consultation.
Schedule a Consultation With Our Aesthetic Injection Specialists
At Skin by Lovely, injectables are an art our specialists have practiced since 2009. Our aesthetic injection specialists focus on facial anatomy day in and day out, bringing a trained eye to balance, proportion and natural-looking results. Skin by Lovely was founded by Lovely Laban, who has personally trained many of the injectors on our team. We use only FDA-approved wrinkle relaxers and fillers, and our patients consistently reflect that care in their reviews.
Ready to find the right wrinkle relaxer for you? Contact us at one of our locations in Camas, WA; Lake Oswego, OR; Portland, OR; or Santa Monica, CA to schedule a consultation.